"This is a book, mind you, that I'd place not only among the greatest science fiction but among our very best novels" - Boston Globe

For Isherwood Williams, his cabin has always been a haven from the demands of society. But one day while hiking, Ish is bitten by a rattlesnake, and the solitude he had so desired takes on dire new significance. Because not long after, the coughing begins. Then the chills and fever and a measles-like rash. He thinks it's a reaction to the bite. What he doesn't know that the venom might be the only thing that kept him alive.

For when Ish heads home the world is not as he left it. No cars pass, the gas station not far from his cabin looks abandoned, there's nothing on the radio, and he is shocked to see the body of a man on the roadside near a small town. He has missed humanity's abrupt demise, only to find himself at the center of society's rebirth. This is a chance to start over, and as Ish gathers survivors to him, he discovers just how wondrous and terrible that proposition is.

And when, decades later, he looks back on his legacy, he is only starting to understand the challenge between enlightenment and practicality. He had left one world, rejoined another, and now leaves--hopefully--an even different world behind. Because, reluctantly or no, his words and actions carry weight for the next generation, and Ish's vision of the future may be one of prophecy...or doom.