In the 25 years since From Neuron to Brain was first published, the authors' aim has remained constant - to describe how nerve cells go about their business of transmitting signals, how the signals are put together, and how, out of this integration, higher functions emerge. The Fourth Edition, while maintaining this focus, has been completely reformatted and updated. The emphasis, as before, is on experiments, and on the way they are carried out. Using a narrative approach, the authors follow a line from the original inception of a new idea to an account of research being done today. The wealth of new facts, techniques, and concepts, however, presented a challenge in keeping the book to a manageable size. Inevitably, the authors have had to delete descriptions of certain classical experiments. Largely in response to readers' comments, elements of format and presentation have been changed for this new edition - more headings have been introduced, the paragraphs are shorter, and the illustrations, now in full color, have been clarified. As in previous editions, references are cited throughout the text, and appendices are provided to help readers unfamiliar with the nervous system deal with essential facts and definitions.