Despite their widespread occurrence, migraines are often misunderstood in terms of both origin and treatment. Migraine Brains and Bodies examines the causes of these painful headaches, many of which can be corrected by the individual. In straightforward language accompanied by detailed illustrations, former migraine sufferer C.M. Shifflett defines the roots and symptoms of migraines as well as the interactions between the source of pain and the rest of the body.

Shifflett begins by dispelling common myths about migraines, contending that they are a symptom of numerous conditions including diet and nutritional inadequacy, infections or autoimmune diseases, sleep disruptions, and impaired muscle function. Explaining that migraines are more likely to come from the shoes and clothes we wear, the furniture we sit in and sleep on, and even the shampoo we use than from brains or genes alone, she discusses migraine triggers and thresholds, points out that some common migraine drugs can make the pain worse, and provides detailed information and advice about various methods of treatment, from physical therapy and massage to acupuncture and biofeedback. She encourage readers to keep food and headache diaries and provides advice for what to do and what not to do when it comes to seeing your doctor.