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Serum Free Light Chain Analysis

Format: Paperback

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There is great interest in using serum free light chain measurements alongside serum protein electrophoresis o screen symptomatic patients for monoclonal gammopathies. The strategy is more sensitive than testing for Bence Jones proteinuria: both simpler and clinically more accurate, Many centres are now using the test in this manner, leading to improvements in patient diagnosis and management. Support for this approach is seen in the emerging International Guidelines for treating patients with multiple myeloma and AI. amyloidosis. Uniform Response criteria have been defined, and patients previously thought to have nonsecretory disease can now enter clinical trials. The full impact of the Free light chains as fast response markers in therapy is yet to be realized. But, in some centres, failure of serum free light chain concentrations to fall rapidly following treatment alterations is interpreted as therapeutic failure. Drug doses of regimens are altered accordingly and ineffective chemotherapy terminated.

Genre: Medical, Immunology
Format: Paperback
Published: 2006
Pages: 285
Publisher: Binding Site Limited
ISBN: 9780704425293

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Our conditions mean the following:

  • New - a brand new book
  • Almost New - appears new but is actually secondhand.
  • Very Good - only minor imperfections such as minor scuffs to edge or cover or a price written in pencil or shop sticker.
  • Standard Secondhand - Clearly been read before, but not too bad. We do not recommend these for gifting. Spines usually creased. Could also include creases or folds to cover, some writing such as in the cover or elsewhere, underlining or highlighting, but might not do. Possibly some stains or marks. Similar in general to books in any secondhand shop or charity shop.
  • Poor Condition - Usually this will have a specific problem such as writing inside, water damage, missing dust jacket, heavy staining, large creases or cuts. These are readable copies but not nice ones. On other websites this condition is called 'Acceptable' or 'Fair' , but we want to be more honest.
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